There are conventional and natural treatments for Osteogenesis Imperfecta and its symptoms. However, a comprehensive treatment program customized to your particular needs is a wise approach.

• Calcium & Vitamin D. Levels of calcium are often high in OI patients. Test calcium and vitamin D levels. Ensure optimal intake, but avoid overdosing.
  
  

• Vitamin C. Incidence of fracturing drops with ongoing vitamin C ingestion.
  
  

• Zinc. Zinc metabolism may be abnormal in OI.
  
  

• Factors and cofactors necessary for collagen production: tyrosine, proline, lysine, Vitamin C, Zn, Cu, Mn, Fe
  
  

• Other nutrients important for bone health: Magnesium, Vitamin K, boron, manganese
  
  

• Chondroitin sulphate is the major glycosaminoglycan (70-80% of total) both in normal and pathological bones, and its level was slightly less in the pathological bones. Glycosaminoglycans have been shown to participate in the formation of a functional super molecular complex in extra cellular matrices. Therefore, they may, in theory, be involved in bone fragility.

While not a common or accepted viewpoint, many of the signs and symptoms of OI have overlap with nutritional deficiencies.