In The US :
The prevalence of OI is estimated to be 1 per 20,000 live births, but the mild form is under diagnosed, and the actual prevalence may be higher than this. There are approximately fifty thousand or more people in the United States alone who have it.

International :
Type I, the most common form of OI, occurs in 1 of 28,500 births. Type II, a rare, lethal form of OI, occurs in 1 of 62,500 births. Type III OI occurs in 1 of 68,800 births. No reliable data exist regarding the frequency of occurrence of type IV OI.

Prevalence appear to be similar worldwide, although an increased rate has been observed in 2 major tribal groups in Zimbabwe.

Race :
Osteogenesis Imperfecta does not seem to have a predilection for any particular race.

Sex :
No differences based on sex are reported.

Age :
The onset of fractures and deformities varies according to the type of Osteogenesis Imperfecta (OI) that is present.

Patients with mild forms may not have fractures until adulthood, or they may present with fractures in infancy. Patients with severe cases present with fractures in utero.