It is compatible with longer life, although people are generally of below-average height, may have skeletal and/or respiratory problems, and brittle teeth.
Type III OI affects 20 percent of the people who have OI. Usually the result of a spontaneous mutation, it is common for a person with this type to have experienced 100 fractures by the time he or she reaches puberty.
Some features of Type III Osteogenesis Imperfecta include:
- Short stature (some people only grow three feet tall).
- Sclera has a blue, purple, or gray tint.
- Soft bones that not only break easily but also bend.
- They have major spinal curvature causing chronic back pain and respiratory problems.
- They will always use a wheelchair for mobility throughout their entire life span.
- Their organs, which are the same size as any normal person’s, are restricted within the smaller rib cage and because of this they experience problems with their organs.
- As with other types of OI, they have a triangular shaped face.
- Poor muscle development.
- Poor tooth development, often causing teeth to be brittle and discolored.
- Possible hearing loss.
- Possible respiratory problems.
- Loose joints and poor muscle development in arms and legs.
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